||Evaluation of the Potential Carcinogenicity of N-Nitrosodimethylamine (62-75-9).
||Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
||EPA-68-03-3112 ;EPA-68-03-3182; EPA/600/8-91/161 ; OHEA-C-073-149
Risk assessment ;
Public health ;
Hazardous materials ;
Dose-response relationships ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
N-Nitrosodimethylamine (also known as dimethylnitrosamine) is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'No Data'. The potency factor (F) for N-nitrosodimethylamine is estimated to be 61.2 (mg/kg/day)-1, placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, N-nitrosodimethylamine is assigned a 'MEDIUM' hazard ranking.