Record Display for the EPA National Library Catalog
RECORD NUMBER: 3 OF 12
|OLS Field Name||OLS Field Data|
|Main Title||Assessment of boric acid and borax using the IEHR evaluative process for assessing human developmental and reproductive toxicity of agents.|
|Author||Moore, J. A.|
|CORP Author||Institutes for Evaluating Health Risks, Washington, DC.;Environmental Protection Agency, Research Triangle Park, NC. National Center for Environmental Assessment.|
|Publisher||U.S. Environmental Protection Agency, National Center for Environmental Assessment,|
|Report Number||EPA/600/R-96/021; EPA-CR-817772-02; OHEA-R-612|
|Additional Subjects||Boric acid ; Borax ; Toxicity ; Health effects ; Boron compounds ; Environmental exposure ; Dose-response relationships ; Pharmacokinetics ; Absorption ; Distribution ; Metabolism ; Males ; Females ; Risk assessment ; Reproduction(Biology) ; Fetal development ; Body weight ; Testes ; Urogenital diseases ; CAS 10043-35-3 ; CAS 1303-96-4|
This document presents an evaluation of the reproductive and developmental effects of boric acid, H3BO3 (CAS Registry No. 10043-35-3) and disodium tetraborate decahydrate or borax, Na2B4O2O(CAS Registry No. 1303-96-4). The element, boron, does not exist naturally. In dilute aqueous solution and at physiological pH (7.4), the predominant species in undissociated boric acid (greater than 98%), irrespective of whether the initial material was boric acid of borax. Therefore, it is both useful and correct to compare exposures and dosages to boric acid and borax in terms of 'boron equivalents', since both materials form equivalent species in dilute aqueous solution with similar systemic effects. In order to be clear in this document, the term 'boron' will refer to 'boron equivalents' or percent boron in boric acid and borax.
"EPA/600/R-96/021." "March 1995." Microfiche.