Record Display for the EPA National Library Catalog

RECORD NUMBER: 7 OF 20

OLS Field Name OLS Field Data
Main Title Evaluation of Normal and Organophosphate and Carbamate Insecticide Inhibited Blood Cholinesterase Activity Utilizing Dimethylbutylacetate as a Substrate.
Author Cranmer, M. F. ; Peoples., A. J. ;
CORP Author Environmental Protection Agency, Chamblee, Ga. Office of Pesticides Programs.
Year Published 1972
Stock Number PB-277 598
Additional Subjects Carbamates ; Cholinesterase inhibitors ; Pesticides ; Insecticides ; Toxicology ; Gas chromatography ; Enzymes ; Blood chemical analysis ; Laboratory animals ; Blood plasma ; Dosage ; Acetates ; Pharmacology ; Acetic acid/butyl-dimethyl ; Reprints ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-277 598 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 1p
Abstract
The availability of an extremely sensitive and precise gas chromatogaphic method for the analysis of human blood cholinesterase led to the attempt to apply this method to common laboratory animals where analysis of limited blood samples is important. The results demonstrate DMBA to be acceptable as a cholinesterase substrate both for the determination of normal and inhibited activities in all species except the mouse, where high levels of nonspecific plasma esterases complicate interpretation.