Record Display for the EPA National Library Catalog

RECORD NUMBER: 13 OF 20

OLS Field Name OLS Field Data
Main Title Multicompartment Kinetic Models for Lead. 1. Bone Diffusion Models for Long-Term Retention.
Author Marcus, A. H. ;
CORP Author Washington State Univ., Pullman. Dept. of Pure and Applied Mathematics.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA/600/J-85/424;
Stock Number PB86-220399
Additional Subjects Lead(Metal) ; Bone ; Models ; Blood plasma ; Dogs ; Reprints ; Kinetic models
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB86-220399 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 20p
Abstract
The long-term retention of lead in bone poses a number of difficulties for the usual multicompartment models. The use of diffusion models based on exchange of lead between blood in canaliculi and the crystalline bone of the osteon allows a linear compartmental approximation suitable for statistical estimation of kinetic parameters in peripheral compartments. The model is applied to lead retention by beagle dogs.