Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Multicompartment Kinetic Model for Lead. Part 3. Lead in Blood Plasma and Erythrocytes.
Author Marcus, A. H. ;
CORP Author Washington State Univ., Pullman. Dept. of Pure and Applied Mathematics.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA/600/J-85/362;
Stock Number PB86-177698
Additional Subjects Lead(Metal) ; Blood plasma ; Mathematical models ; Concentration(Composition) ; Erythrocytes ; Reprints ; Kinetic models
Library Call Number Additional Info Location Last
NTIS  PB86-177698 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 19p
Multicompartment models have been fitted to experimental data on plasma lead and blood lead concentrations of subjects studied by de Silva (1981, Brit. J. Industr. Med. 38, 209-217) and one subject studied by Manton and Malloy (1983, Brit. J. Industr. Med., 40, 51-57). Nonlinear models for plasma lead vs. blood lead in populations provide significantly better descriptions than does a linear model. Short-term kinetic data do not clearly resolve the precise nonlinear mechanism, however. Parameters of plasma and erythrocyte distribution in a single subject were significantly different on two occasions.