Record Display for the EPA National Library Catalog
RECORD NUMBER: 24 OF 66
|OLS Field Name||OLS Field Data|
|Main Title||Determination of Metabolic and Hydrolytic Products of Organophosphorus Pesticide Chemicals in Human Blood and Urine.|
|Author||Shafik, M. T. ; Enos., H. F. ;|
|CORP Author||Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.|
|Stock Number||PB-276 904, PB-276 897|
|Additional Subjects||Pesticides ; Phosphorus organic compounds ; Blood analysis ; Urine ; Chemical analysis ; Hydrolysis ; Metabolism ; Insecticides ; Humans ; Extraction ; Gas chromatography ; Reprints|
The procedure of St. John and Lisk for the determination of the hydrolytic metabolites of organophosphorus insecticides in cow urine has been modified for application to human blood and urine. The interference from inorganic phosphates was eliminated by making the methyl and ethyl derivatives of the dialkyl phosphates. The use of a column packed with 20% Versamid on Gas Chrom Q allowed for the simultaneous determination of the six major metabolites of organophosphorus and thiophosphorus insecticides. The level of alkyl phosphates excreted in the urine of exposed individuals was considerably higher than in the nonexposed group.
found in PB-276 897 titled: Journal articles on pesticide chemical analysis. Group 5.