The AQUIRE (AQUatic toxicity Information REtrieval) database was established in 1981 by the United States Environmental Protection Agency (US EPA), Environmental Research Laboratory-Duluth (ERL-D). The purpose of AQUIRE is to provide quick access to a comprehensive, systematic, computerized compilation of aquatic toxic effects data. As of July 1992, AQUIRE consists of over 98,300 individual test results on computer file. These tests contain information for 5,500 chemicals and 2,300 organisms, extracted from over 6,300 publications. In addition, the ERL-D data file, prepared by the University of Wisconsin-Superior is now included in AQUIRE. The data file consists of acute toxicity test results for the effects of 525 organic chemicals to fathead minnow. All AQUIRE data entries have been subjected to established quality assurance procedures.