Main Title |
Guidelines for reproductive toxicity risk assessment : draft. |
Author |
Clegg., E.
|
Other Authors |
|
CORP Author |
Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, |
Year Published |
1994 |
Report Number |
EPA/600-AP-94-001; OHEA-R-558 |
Stock Number |
PB94-155827 |
OCLC Number |
30047996 |
Subjects |
Reproductive toxicology--Government policy ;
Human reproduction--Effect of chemicals on ;
Health risk assessment
|
Additional Subjects |
Toxicity ;
Risk assessment ;
Reproduction(Biology) ;
Testings ;
Males ;
Females ;
Exposure ;
Biological accumulation ;
Fertility ;
Dose-response relationships ;
Biological markets ;
Histology
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EHBD |
EPA/600/AP-94/001 |
|
CEMM/ACESD Library/Narragansett,RI |
02/16/2007 |
EJED |
EPA 600/AP-94/001 |
|
OCSPP Chemical Library/Washington,DC |
04/01/1994 |
EKBD |
EPA/600/AP-94/001 |
|
Research Triangle Park Library/RTP, NC |
04/15/1994 |
EKCD |
EPA/600/AP-94/001 |
|
CEMM/GEMMD Library/Gulf Breeze,FL |
10/02/2018 |
ELBD ARCHIVE |
EPA 600-AP-94-001 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
ERAD |
EPA 600/AP-94-001 |
|
Region 9 Library/San Francisco,CA |
01/01/1988 |
ESAD |
EPA 600-AP-94-001 |
|
Region 10 Library/Seattle,WA |
01/02/1998 |
NTIS |
PB94-155827 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
vi, 134 pages ; 28 cm |
Abstract |
In 1988, EPA published separate Proposed Guidelines for Assessing Male Reproductive Risk and Proposed Guidelines for Assessing Female Reproductive Risk. Changes made based on previous public comment and SAB review include combining the separate guidelines for assessing male and female reproductive risk into a single document, integrating the hazard identification and dose-response sections, assuming as a default that an agent for which sufficient data are available on only one sex may also affect reproductive function in the other sex, expansion of the section on interpretation of female endpoints, and consideration of the benchmark dose approach for quantitative risk assessment. This external review draft document will be revised after public review and comment. |
Notes |
"Draft, do not quote or cite." "EPA/600-AP-94-001." "February 1994." "This external review draft was prepared by an intra-Agency EPA working group chaired by Eric Clegg of the Office of Health and Environmental Assessment"--Page vi. |