Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Molecular Biology of Metal Homeostasis and Detoxification From Microbes to Man / [electronic resource] :
Author Tamas, Markus J.
Other Authors
Author Title of a Work
Martinoia, Enrico.
Publisher Springer Berlin Heidelberg : Imprint: Springer,
Year Published 2006
Call Number QD415-436
ISBN 9783540317197
Subjects Life sciences. ; Medicine. ; Biochemistry. ; Cytology. ; Microbiology. ; Plant physiology.
Internet Access
Description Access URL
Collation XX, 509 p. online resource.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.