||Health Assessment for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds. Chapter 2. Mechanisms of Toxic Actions.
Whitlock, J. ;
||Syracuse Research Corp., NY. ;Stanford Univ., CA. School of Medicine.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
||EPA-68-C0-0043; EPA/600/AP-92/001B ; OHEA-I-486-VOL-2
Public health ;
Risk assessment ;
Binding sites ;
Biological effects ;
Aryl hydrocarbon receptors ;
Biological response ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
Knowledge of the mechanisms of TCDD action may facilitate the risk assessment process by imposing constraints upon the assumptions used to estimate an acceptable exposure to dioxin. The chapter reviews the current knowledge of dioxin action, with emphasis on the contribution of the Ah receptor to the mechanism.