Record Display for the EPA National Library Catalog
RECORD NUMBER: 343 OF 1241
|OLS Field Name||OLS Field Data|
|Main Title||Content of platinum and palladium in rat tissues : correlation of tissue concentrations of platinum and palladium with biochemical effects /|
|Author||Holbrook, David J.|
|CORP Author||North Carolina Univ. at Chapel Hill. Dept. of Biochemistry.;Health Effects Research Lab., Research Triangle Park, N.C.|
|Publisher||U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,|
|Report Number||EPA/600/1-77/051; EPA-Z804557-01|
|Stock Number||PB-275 522|
|Subjects||Platinum--Physiological effect. ; Palladium--Physiological effect.|
|Additional Subjects||Platinum ; Palladium ; Toxicology ; Air pollution ; Motor vehicles ; Exhaust emissions ; Diets ; Ingestion(Biology) ; Tissues(Biology) ; Deposition ; Metabolism ; Drugs ; Biochemistry ; Body weight ; Dose rate ; Rats ; Laboratory animals ; Bioassay ; Proteins ; Metals ; Chemical bonds ; Environmental health ; Catalytic converters ; Air pollution control equipment ; Air pollution effects(Animals)|
|Collation||vi, 14 pages ; 28 cm.|
Platinum and palladium are used as the active components in the catalytic converters of air pollution control devices of motor vehicles. The use of these metals is accompanied by the potential loss of platinum and palladium into the environment. This laboratory has been involved in studies on the biochemical effects of these metals. Data have been compiled on the platinum and palladium content in six rat tissues after the dietary administration of platinum or palladium salts. The platinum and palladium content in rat tissues does not appear to correlate with the rates of weight gain of rats, the organ weights, or the four parameters of drug metabolism which were studied.
"EPA-600/1-77-051." EPA contract no. Z804557-01; EPA project officer: M.F. Copeland. Includes bibliographical references (page 13). Microfiche.