Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Estimation of Molecular Diffusivity in Isolated Animal Tissues.
Author Shirazi, M. A. ; Riley, R. T. ;
CORP Author Corvallis Environmental Research Lab., OR.
Year Published 1981
Report Number EPA-600/J-81-557;
Stock Number PB82-223884
Additional Subjects Tissues(Biology) ; Diffusivity ; Toxicology ; Animals ; Kinetics ; Transport ; Diffusion ; Body fluids ; Concentration(Composition) ; Reprints ; Bioaccumulation ; Biodeterioration
Library Call Number Additional Info Location Last
NTIS  PB82-223884 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 6p
If molecular transport of a lipophilic toxicant in isolated tissues is truly a diffusion process, then it should be possible to describe the process in terms of mathematical equations commonly used to describe the conduction of heat in homogenous and isotropic solids. The present approach compares well with other more direct and empirical methods for estimating diffusivity and it has the advantage that diffusivity so calculated is biologically realistic. The ability to evaluate toxicant uptake by organs of various sizes is theoretically factored in the method. Likewise, the physiological characteristics as a whole are factored by using the empirical data directly consistent with the stated theoretical framework.