Record Display for the EPA National Library Catalog

RECORD NUMBER: 985 OF 1029

OLS Field Name OLS Field Data
Main Title Teratogenic Evaluation and Fetal Deposition of Hexabromobenzene (HBB) and Hexafluorobenzene (HFB) in CD-1 Mice.
Author Courtney, K. D. ; Andrews, J. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-600/J-84-013;
Stock Number PB84-197573
Additional Subjects Bioassay ; Mice ; Laboratory animals ; Dosage ; Concentration(Composition) ; Reprints ; Benzene/hexabromo ; Benzene/hexafluoro ; Teratogenesis
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB84-197573 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 14p
Abstract
HBB (hexabromobenzene) and HFB (hexafluorobenzene) were tested for their teratogenic potential in CD-1 mice. HBB and HFB were administered to pregnant mice from the 6th to the 16th day of gestation by gastric intubation. Neither HBB nor HFB were teratogenic or fetotoxic at doses up to 98.6 mg HBB/kg and 65.3 mg HFB/kg. No maternal toxicity was noted. HBB concentration in the fetuses indicated little, if any, accumulation. No HFB was detected in the fetal or maternal tissues 24 hours after the last dose.