Record Display for the EPA National Library Catalog
RECORD NUMBER: 137 OF 428
|OLS Field Name||OLS Field Data|
|Main Title||Experimental Design and Data Analysis Applicable to Assays for Monitoring Waterborne Viruses.|
|Author||Wymer, L. J. ;|
|CORP Author||Computer Sciences Corp., Falls Church, VA.;Environmental Monitoring Systems Lab., Cincinnati, OH.|
|Additional Subjects||Experimental design ; Viruses ; Statistical analysis ; Bioassay ; Poisson density functions ; Data acquisition ; Environmental tests ; Water chemistry ; Quality assurance ; Plaque assay|
Techniques are presented for the statistical treatment of data obtained from single titration plaque count viral assays. It is recommended that the standard statistical analysis of any such assay include a test for Poisson distribution of the plaque counts and interval estimates for titer (in total and by virus type), and proportions represented by virus types in the sample. Techniques for improving the quality of the data are discussed, including suggestions to type all viruses from selected bottles rather than randomly selecting plaques for typing, sample size guidelines, and measures to be taken to optimize the precision of the assay.