This document presents a recommended framework for investigating and characterizing the potential for human exposure from asbestos contamination in outdoor soil and indoor dust at Superfund removal and remedial sites. This document is one piece of broader intra- and inter- Agency efforts to utilize recent developments regarding asbestos so that current scientific information can be used to better assess exposure and risk from asbestos (e.g., Agency efforts to update cancer and non-cancer assessments for asbestos). The recommended framework presented herein provides a process that supplements other EPA guidance concerning exposure and risk assessment, and is specific to assessment of sites contaminated with asbestos. This recommended framework is needed because there are a number of unique scientific and technical issues associated with the investigation of human exposure and risk from asbestos, and it is important for risk assessors and risk managers to understand these issues when performing assessments of asbestos sites. This recommended framework discusses specific strategies that are based on the best available science and recommends common industrial hygiene methods for characterizing exposure and risk from asbestos.