Record Display for the EPA National Library Catalog
RECORD NUMBER: 18 OF 51Main Title | Evaluation of the potential carcinogenicity of benzidine and its salt (92-87-5) / | |||||||||||
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CORP Author | Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
Year Published | 1988 | |||||||||||
Report Number | EPA/600/8-91/072; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-030 | |||||||||||
Stock Number | PB93-184976 | |||||||||||
Subjects | Aromatic compounds--Carcinogenicity ; Benzidine--Carcinogenicity | |||||||||||
Additional Subjects | Benzidine ; Toxicity ; Risk assessment ; Public health ; Exposure ; Neoplasms ; Hazardous materials ; Tolerances(Physiology) ; Carcinogenicity ; Dose-response relationships ; CAS Registry No: 92-87-5 | |||||||||||
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Collation | 25 pages ; 28 cm | |||||||||||
Abstract | Benzidine is a human carcinogen, classified as weight-of-evidence Group A under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient,' and the evidence from human studies is 'Sufficient.' The potency factor (F) for benzidine is estimated to be 2220 (mg/kg/day)(-1) (derived from human epidemiology data), placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, benzidine is assigned a 'HIGH' hazard ranking. |
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Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |