Record Display for the EPA National Library Catalog

RECORD NUMBER: 25 OF 58

OLS Field Name OLS Field Data
Main Title Evaluation of the potential carcinogenicity of streptozotocin (18883-66-4) /
CORP Author Environmental Monitoring and Services, Inc., Washington, DC. ;Syracuse Research Corp., NY.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;
Year Published 1988
Report Number EPA/600/8-91/180; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-175
Stock Number PB93-201275
Subjects Streptozotocin--Carcinogenicity.
Additional Subjects Streptozocin ; Antibiotics ; Toxicity ; Risk assessment ; Public health ; Exposure ; Hazardous materials ; Neoplasms ; Tolerances(Physiology) ; Carcinogenicity ; Dose-response relationships ; CAS: 18883-66-4
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB93-201275 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 19 pages ; 28 cm
Abstract
Streptozotocin (also streptozocin) is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Sufficient', and the evidence from human studies is 'No Data'. The potency factor (F) for streptozotocin is estimated to be 109 (mg/kg/day)-1, placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, streptozotocin is assigned a 'HIGH' hazard ranking.
Notes
Cover title. "June 1988." Includes bibliographical references. Microfiche.