Record Display for the EPA National Library Catalog

RECORD NUMBER: 22 OF 58

OLS Field Name OLS Field Data
Main Title Effects of Segregation and Selection on Instability of Plasmid pACYC184 in 'Escherichia coli'B.
Author Lenski, R. E. ; Bouma, J. E. ;
CORP Author California Univ., Irvine. Dept. of Ecology and Evolutionary Biology.;Environmental Research Lab., Gulf Breeze, FL.
Year Published 1987
Report Number EPA-R-813401; EPA/600/J-87/311;
Stock Number PB88-196241
Additional Subjects Tolerances(Physiology) ; Bacteria ; Cell division ; Antibiotics ; Escherchi coli ; Mathematical models ; Selection ; Deoxyribonucleic acids ; Populations ; Dynamics ; Plasmids ; Hosts
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB88-196241 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 09/04/1988
Collation 5p
Abstract
The authors use a mathematical model to analyze the dynamics of loss of nonconjugative pACYC184 from populations of Escherichia coli B in glucose-limited continuous culture. The model incorporates both plasmid segregation and selection against plasmid carriage. It is concluded that there is intense selection against plasmid carriage (s = 0.3 per culture generation), which amplifies the frequency of segregants arising de novo. (Copyright (c) 1987, American Society for Microbiology.)