Record Display for the EPA National Library Catalog
RECORD NUMBER: 36 OF 57Main Title | Approaches to Lung Function Assessment in Small Mammals. | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Author | Costa, D. L. ; Tepper, J. S. ; | |||||||||||
CORP Author | Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. | |||||||||||
Year Published | 1987 | |||||||||||
Report Number | EPA-68-02-4032; EPA/600/D-87/225; | |||||||||||
Stock Number | PB87-212718 | |||||||||||
Additional Subjects | Lung ; Laboratory animals ; Toxicology ; Exposure ; Animal physiology ; Pressure ; Ventilation ; Measurement ; Response ; Anesthetics ; Volume ; | |||||||||||
Holdings |
|
|||||||||||
Collation | 70p | |||||||||||
Abstract | The review chapter of pulmonary function assessment in small mammals first discusses basic principles and methods such as assessment of various pressures, volumes and flows. The three types of plethysmographs (pressure, flow and barometric) used by animal physiologists are evaluated with special reference to frequency and phase response. A review of ventilatory measurements, usually obtained in unanesthetized animals, is presented. Topics discussed in this section include: anesthesia, restraint, sensory irritation, pulmonary mechanics, airway reactivity, double plethysmography and control of ventilation. |