Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Latency Strategies of Herpesviruses [electronic resource] /
Author Minarovits, Janos.
Other Authors
Author Title of a Work
Gonczol, Eva.
Valyi-Nagy, Tibor.
Publisher Springer US,
Year Published 2007
Call Number QR355-502
ISBN 9780387341279
Subjects Medicine. ; Immunology. ; Medical virology. ; Veterinary medicine. ; Microbiology. ; Bacteriology. ; Animal genetics.
Internet Access
Description Access URL
Collation XII, 297 p. online resource.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Latency Strategies of Alphaherpesviruses: Herpes Simplex Virus and Varicella-Zoster Virus Latency in Neurons -- Modulation of Apoptotic Pathways by Herpes Simplex Viruses -- Cytomegalovirus Latency -- Human Herpesvirus 6 and Human Herpesvirus 7 -- Murid Herpesvirus 4 (MuHV-4): An Animal Model for Human Gammaherpesvirus Research -- Latency Strategies of Equine Herpesviruses -- The Multifunctional Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus -- Epstein-Barr Virus. Latency is a fascinating property of herpesviruses which ensures the maintenance of their genetic information in their hosts for an extended period in the absence of productive virus replication. Focusing on human herpesviruses and animal models of herpesvirus-associated human diseases, this is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation. Latency Strategies of Herpesviruses is an ideal book for researchers, scientists and graduate students in the fields of virology, immunology, microbiology, bacteriology, and veterinary medicine.