Record Display for the EPA National Library Catalog

RECORD NUMBER: 4 OF 8

OLS Field Name OLS Field Data
Main Title Issues That Must Be Addressed When Constructing Anatomical Models of the Developing Lung.
Author Menache, M. G. ; Graham, R. C. ;
CORP Author Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1988
Report Number EPA-68-02-4450; EPA/600/D-88/023;
Stock Number PB88-170790
Additional Subjects Anatomical models ; Lung ; Air pollution ; Dimensional analysis ; Respiration ; Contaminants ; Toxicity ; Dosimetry ; Air pollution effects(Humans) ; Airway resistance
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB88-170790 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 32p
Abstract
Published data on airway dimensions in the developing human lung, including estimated age-dependent changes and experimental data, have been summarized to illustrate the variability and gaps in the data used to develop anatomical models for deposition calculations. A comparison of the morphological dimensions resulting from various assumptions about the volume distribution of pulmonary airways is also presented. Although deposition is not examined here, the varibility in reported measurements underscores the influence that anatomical parameters can have on deposition calculations and the importance of further investigation of lung dimensions to reduce the uncertainties in computer simulations of delivered dose, thereby improving the data base necessary for risk assessment.