Record Display for the EPA National Library Catalog

RECORD NUMBER: 6 OF 6

OLS Field Name OLS Field Data
Main Title Structure-Activity Relationships in Developmental Toxicology.
Author Kavlock, R. J. ;
CORP Author Health Effects Research Lab., Cincinnati, OH.
Year Published 1988
Report Number EPA/600/D-88/125;
Stock Number PB88-218458
Additional Subjects Toxicology ; Chemical compounds ; Chemical reactivity ; Molecular structures ; Aliphatic acids ; Phenols ; Fungicides ; Retinoids
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB88-218458 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 12/29/1988
Collation 12p
Abstract
As in other related disciplines, researchers in developmental toxicology have pursued the goal of defining structure-activity relationships within chemical classes. Due to the inherent complexity of developmental processes, however, it has often been difficult to find significant and predictive relationships between biological activity and chemical structure in the area. The review covers four examples of such efforts. Each approached the problem with different levels of experimental or statistical sophistication. Finally, comments are provided on how future research efforts may be constructed to improve the probability of overall success.