Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title General Principles for Performing Aggregate Exposure and Risk Assessments.
CORP Author Environmental Protection Agency, Washington, DC. Office of Pesticide Programs.
Publisher 28 Nov 2001
Year Published 2001
Stock Number PB2005-102091
Additional Subjects Environmental exposure pathways ; Pesticides ; Agglomeration ; Risk assessment ; Food ; Drinking water ; Chemical analysis ; Pesticide residues ; Toxicity ; Ingestion ; Inhalation ; Routes ; Absorption ; Regulations ; Dermal exposure ; Humans ; Guidance ; Aggregate exposure
Library Call Number Additional Info Location Last
NTIS  PB2005-102091 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 05/04/2005
Collation 84p
Office of Pesticide Programs (OPP) is responsible for regulating pesticide residues in food under the Federal Food, Drug, and Cosmetic Act (FFDCA). In 1996, Congress passed the Food Quality Protection Act (FQPA) which amended FFDCA. The FQPA amendments to the FFDCA directed OPP to consider aggregate exposure in its decision-making. Aggregate exposure and risk assessment involve the analysis of exposure to a single chemical by multiple pathways and routes of exposure. The pathways of exposure considered in this general principles document include the potential for pesticide residues in food and drinking water, as well as residues from pesticide use in residential, nonoccupational environments. The pathway of exposure refers to how human behavioral patterns potentially interact with pesticides in the environment. All potential, relevant routes of exposure are analyzed within an aggregate exposure assessment. These include the oral, dermal (absorption), and inhalation routes of exposure. Thus, OPP was required by the FQPA amendments to modify its exposure and risk assessment methods to consider that pesticide chemicals may enter the body through various pathways (through food, drinking water, and residential uses) and routes (ingestion, dermal, and inhalation).