Record Display for the EPA National Library Catalog
RECORD NUMBER: 48 OF 3451
|OLS Field Name||OLS Field Data|
|Main Title||Acute Inhalation Toxicity in Rats Using Dibutylamine: One Hour Exposure.|
|CORP Author||Huntingdon Research Centre PLC (England).; Pennwalt Corp., King of Prussia, PA.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; Dibutylamine (111-92-2) ; Acute Toxicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 111-92-2|
Acute inhalation toxicity was evaluated in 5 male and 5 female Sprague-Dawley albino rats exposed to dibutylamine at an actual concentration of 573 ppm for 1 hour. Mortality was not observed; the LC50 value was reported to be > 573 ppm. Clinical observations included partial closing of eyes, reduced respiratory rate, exaggerated respiratory movements, hunched body posture, and ataxia. Gross necropsy revealed no abnormalities.