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RECORD NUMBER: 35 OF 3451

OLS Field Name OLS Field Data
Main Title Acute Dermal Toxicity Study of P-tert-butylbenzoic Acid on Rats with Attacments and Cover Letter Dated 07/23/1987.
CORP Author Hoechst Celanese Corp., Summit, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1987
Report Number 86-870000806
Stock Number OTS0515244
Additional Subjects Toxicology ; Health effects ; 4-(1 ; 1-dimethylethyl)benzoic Acid (98-73-7) ; Acute Toxicity ; Mammals ; Rats ; Dermal ; Toxic substances ; Laboratory animals ; CAS No 98-73-7
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NTIS  OTS0515244 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 13p
Abstract
Acute dermal toxicity was evaluated in 6 female SPF Wistar rats receiving single occluded applications of paratertiary butylbenzoic acid at a dose level of 2000 mg/kg of body weight. The test article was held in contact with the intact skin for a period of 24 hours. Mortality was observed within 14 days of treatment in 1 animals; the LD50 was determined to be greater than 2000 mg/kg of body weight. Clinical observations included disequilibrium problems and no signs of irritation. Weight loss was noted in some of the animals. Gross necropsy was not reported.