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RECORD NUMBER: 151 OF 3451

OLS Field Name OLS Field Data
Main Title Aerothene Tt Solvent: Acute Inhalation Toxicity Test with Attachments and Cover Letter Dated 11/20/1987.
CORP Author Mellon Inst.-Union Carbide Corp., Export, PA. Bushy Run Research Center.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1987
Report Number 86-880000083
Stock Number OTS0513973
Additional Subjects Toxicology ; Health effects ; Aerothene Tt Solvent (71-55-6) ; Acute Toxicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 71-55-6
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NTIS  OTS0513973 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 27p
Abstract
Acute inhalation toxicity was evaluated in groups of 5 male and 5 female Sprague-Dawley albino rats exposed to Aerothene TT (1,1,1-trichloroethane) as a vapor (dynamically-generated) at an actual concentration of 34,134 mg/cubic meter or as a vapor/aerosol (fine mist sprayed into a pre-atomization chamber) at an actual concentration of 19,265 mg/cubic meter for 4 hours. Mortality was observed in 4 males and 3 females in the vapor/aerosol dose group (19,265 mg/cubic meter). An LC50 value was not reported. Clinical observations included hypoactivity in animals exposed to the vapor and abdominal breathing, decreased respiration rate and hypoactivity in animals exposed to the vapor/aerosol. Gross necropsy revealed dark red discoloration of the lungs, fluid in the thoracic cavity and trachea, red perinasal, perioral, or periocular encrustation, and gas-filled intestines in decedents.