Main Title |
Telomerase inhibition strategies and protocols / [Texte imprimâe] : |
Author |
Andrews, Lucy G.
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Other Authors |
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Publisher |
Humana ; Quantum [distributor], |
Year Published |
2007 |
OCLC Number |
494822868 |
ISBN |
9781597455015; 1597455016; 9781588296832; 1588296830 |
Subjects |
Telomerase--Inhibitors ;
ADN nuclâeotidylexotransfâerase
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Internet Access |
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Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
ELBM |
QP606.T44A537 2007 |
|
AWBERC Library/Cincinnati,OH |
02/01/2016 |
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Collation |
1 volume (X-193 pages) ; 23 cm. |
Notes |
Includes bibliographical references and index. |
Contents Notes |
Methods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect. |