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OLS Field Name OLS Field Data
Main Title Ames Salmonella/mammalian Microsome Mutagenicity Test and Reverse Mutation Assay - E. Coli Wp2 Uvra a (Standard Plate Test and Preincubation Test) (Oct. 19, 1988) W-letter 12/16/1991.
CORP Author BASF A.G., Limburgerhof (Germany, F.R.). Agricultural Research Station.; BASF Corp., Mount Olive, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1991
Report Number 86-920000590
Stock Number OTS0535474
Additional Subjects Toxicology ; Health effects ; 4-methylbenzaldehyde (104-87-0) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 104-87-0
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NTIS  OTS0535474 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 32p
Abstract
P-Tolualdehyde (CAS No. 104-87-0) was evaluated for mutagenicity in the Ames test (strains TA1535, TA100, TA1537, TA98) with and without metabolic activation (S-9 mix) and in the Escherichia coli (WP2 uvrA) reverse mutation assay at a dose range of 20 ug - 5000 ug/plate in the standard plate test (SPT) and 4 ug - 2500 ug/plate in the preincubation test (PIT). No bacteriotoxic effect was observed with E. coli. Bacteriotoxicity was detected in all Salmonella strains detected at 2500 ug/plate (PIT) and at 5000 ug/plate (SPT). The test substance was determined to be non- mutagenetic.