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RECORD NUMBER: 6 OF 17

OLS Field Name OLS Field Data
Main Title Initial Submission: Letter from Confidential Source to USEPA Reporting Neurotoxicity in Acute Inhalation Toxicity Study in Rats of Cyclopropanecarboxylic Acid, 3-(2-chloro-3, 3,3-trifluoro-1- propenyl)-2,2-dimethyl cyano(3-phenoxyphenyl)methyl ester,(1R-(1.alpha.(s(asterick), 3.alpha.(Z)))) dated 12/14/99. (Sanitized).
CORP Author ; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1999
Report Number 8EHQ-1299-14614S
Stock Number OTS0559861
Additional Subjects Toxicology ; Neurotoxicity ; Rats ; Health effects ; Inhalation ; Acute toxicity ; Males ; Females ; Laboratory animals ; Mammals ; Test methods ; Tremors ; Toxic substances ; Cyclopropanecarboxylic acid ; CAS No 76703-62-3 ; 3 ; (2-chloro-3 ; 3 ; 3-trifluoro-1-propenyl)
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NTIS  OTS0559861 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 04/28/2010
Collation 5p
Abstract
Groups of 5 male and 5 female Wistar Han rats were administered the test material by inhalation for four hours to a time-weighted average chamber concentration of 35.1 mg/m3 and were observed for 14 days. Three males and two females survived the observation period. Neurologic toxicity was observed in all surviving animals. Observations included incoordination, inability to walk and one female had tremors.