Record Display for the EPA National Library Catalog

RECORD NUMBER: 8 OF 11

OLS Field Name OLS Field Data
Main Title Mutagenicity Evaluation of Isobutanol Alcohol in the Ames Salmonella/Mmicrosome Plate Test (Final Report) with Cover Letter Dated 03/11/1987.
CORP Author Litton Bionetics, Inc., Bethesda, MD.; Celanese Chemical Co., Bishop, TX.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1987
Report Number 86870000238
Stock Number OTS0513188
Additional Subjects Toxicology ; Health effects ; 2-methyl-1-propanol (78-83-1) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 78-83-1
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NTIS  OTS0513188 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/10/2010
Collation 13p
Abstract
The mutagenicity of isobutyl alcohol was evaluated in Salmonella tester strains TA1535, TA1537, TA1538, TA98 and TA100 and the yeast Saccharomyces cerevisiae D4, both in the presence and absence of Aroclor-induced rat liver S9 fraction. Isobutyl alcohol, diluted with DMSO, was tested for mutagenicity at concentrations of 0.001, 0.01, 0.1, 1.0 and 5.0 ul/plate using the agar incorporation method. Isobutyl alcohol did not produce a positive response in any bacterial tester strain, either with or without metabolic activation.