Main Title |
Drug toxicokinetics |
Other Authors |
|
Publisher |
M. Dekker, |
Year Published |
1993 |
OCLC Number |
27813419 |
ISBN |
0824790197 (alk. paper) |
Subjects |
Drugs--Toxicology ;
Pharmacokinetics ;
Drugs--toxicity ;
Pharmacokinetics
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EKBM |
RA1238.D8 1993 |
|
Research Triangle Park Library/RTP, NC |
02/21/2006 |
|
Collation |
xviii, 408 p. : ill., charts ; 24 cm. |
Notes |
Includes bibliographical references and index. |
Contents Notes |
Analytical method considerations for toxicokinetic studies / D. Scott Wright -- Pharmacokinetic principles: linear and nonlinear / Peter G. Welling -- Biotransformation of xenobiotics to chemically reactive metabolites / Neal Castagnoli, Jr. and Kay P. Castagnoli -- Role of toxicokinetics in dose selection for carcinogenicity studies / Mitchell N. Cayen and Hugh E. Black -- Toxicokinetic study design and integrated programs / Eva Halperin-Walega, Avraham Yacobi and Vijay K. Batra -- Role of toxicokinetics in toxicity testing / L.F. Chasseaud -- Relation between toxicity and kinetics and models of renal disease / Norberto Perico and Silvio Garattini -- Route of administration and toxicity / Lloyd A. Dethloff -- Genetic variations in humans and toxicokinetics / Bert N. La Du, Jr. -- Comparative histokinetic and xenodynamic considerations in toxicity / Michael J. Iatropoulos -- Toxicokinetics of anticancer compounds / Lloyd R. Whitfield and David G. Pegg -- Toxicokinetics of chemical carcinogens / Anthony J. Streeter. (cont.) Application of toxicokinetic principles in the development of antiatherosclerotic compounds / Robert L. Susick and Thomas Woolf -- Toxicokinetics of drugs acting on the central nervous system / D. Scott Wright, Steven E. Rose and John R. MacDonald -- Toxicokinetics of antibacterial agents: preclinical perspective / Robert D. Smyth and Robert J. Smyth -- Perspective and future directions of toxicokinetics in drug development / Felix A. de la Iglesia. |