Record Display for the EPA National Library Catalog

RECORD NUMBER: 12 OF 12

OLS Field Name OLS Field Data
Main Title Method for the Determination of Dialkyl Phosphate Residues in Urine.
Author Reid, Stuart J. ; Watts, Randall R. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Environmental Toxicology Div.
Year Published 1981
Report Number EPA-600/J-81-151;
Stock Number PB82-124264
Additional Subjects Pesticides ; Urine ; Chemical analysis ; Organic phosphates ; Exposures ; Public health ; Gas chromatography ; Residues ; Concentration(Composition) ; Reprints ; Phosphoric acid/(dimethyl-ester) ; Phosphoric acid/(diethyl-ester) ; Phosphorothionic acid/(dimethyl-ester) ; Phosphorodithioic acid/(dimethyl-ester) ; Phosphorthionic acid/(diethyl-ester) ; Phosphorodithioic acid/(diethyl-ester)
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB82-124264 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 9p
Abstract
The analysis of urine for dialkyl phosphate residues provides a measure of mammalian exposure to organophosphate pesticides. A method is presented for quantitative determination of six alkyl phosphate urinary metabolites. These metabolites are as follows: 0,0-dimethyl phosphate, 0,0-diethyl phosphate, 0,0-dimethyl phosphorothionate, 0,0-dimethyl phosphorodithioate, 0,0-diethyl phosphorthionate, and 0,0-diethyl phosphorodithioate. A screening method is also given for a rapid assessment of human exposure. Pentafluorobenzyl bromide is utilized as the derivatization reagent to form pentafluorobenzyl esters. The reaction products are determined by gas chromatography on routine pesticide columns utilizing the phosphorus specific flame photometric detector. Recoveries of all six dialkyl phosphates are greater than 90% with the minimum level of detection ranging from 0.04 to 0.13 ppm.