Record Display for the EPA National Library Catalog

RECORD NUMBER: 8 OF 11

OLS Field Name OLS Field Data
Main Title Kinetic Study on the Inhibition of Hen Brain Neurotoxic Esterase by Mipafox.
Author Soliman, Salah A. ; Curley, August ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-600/J-81-236;
Stock Number PB83-209692
Additional Subjects Inhibitors ; Esterases ; Chickens ; Brain ; Reprints ; Mipafox ; Neurotoxins ; Valerate/nitrophenyl
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB83-209692 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 7p
Abstract
A direct method of assaying neurotoxic esterase (NTE) activity, using 4-nitrophenyl valerate, has been described. The technique was used to determine the biomolecular rate (ki), phosphorylation (k2), and affinity (kd) constants for the reaction of hen brain microsomal NTE with mipafox. Results indicate that the new technique for assaying NTE makes detailed kinetic studies of NTE inhibition possible.