Record Display for the EPA National Library Catalog

RECORD NUMBER: 28 OF 55

OLS Field Name OLS Field Data
Main Title Dominant Lethal Effects of Subchronic Acrylamide Administration in the Male Long-Evans Rat.
Author Smith, M. K. ; Zenick, H. ; Preston, R. J. ; George, E. L. ; Long, R. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Cincinnati Univ., OH. Dept. of Environmental Health. ;Oak Ridge National Lab., TN.
Year Published 1986
Report Number EPA/600/J-86/059;
Stock Number PB86-204633
Additional Subjects Toxicology ; Bioassay ; Vinyl ; Dosage ; Acrylamide ; Neurotoxicity
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB86-204633 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 7p
Abstract
Acrylamide, a widely used vinyl monomer, is well known as a neurotoxin but inactive as a mutagen in bacterial test systems. The experiments reported demonstrate that after subchronic oral dosing in the male rat, acrylamide induced significant elevations in both pre and post implantation loss following dominant lethal testing. These effects were seen at doses which failed to produce clinical or pathological evidence of neurotoxicity.