Main Title |
Peroxyacetyl Nitrate: Measurement of Its Mutagenic Activity Using the 'Salmonella'/Mammalian Microsome Reversion Assay. |
Author |
Kleindienst, T. E. ;
Shepson, P. B. ;
Edney, E. O. ;
Claxton, L. D. ;
|
CORP Author |
Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1985 |
Report Number |
EPA/600/J-85/237; |
Stock Number |
PB86-136181 |
Additional Subjects |
Bacteria ;
Toxicology ;
Exposure ;
Concentration(Composition) ;
Reprints ;
Salmonella typhimurium ;
CAS 2278-22-0 ;
Peroxyacetyl nitrate ;
Mutagenesis
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-136181 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
7p |
Abstract |
Exposures of Salmonella typhimurium strain TA100, with and without S9 metabolic activation, to low ppm levels of pure peroxyacetyl nitrate (PAN) in the gas phase were conducted. Measurements of the gas phase PAN exposure concentration and the concentration of its decomposition products in surrogate test media led to a measured mutagenic activity of 34 plus or minus 5 revertants/micromoles. The data indicated that PAN is a relatively weak direct-acting mutagen with TA100. |