Record Display for the EPA National Library Catalog

RECORD NUMBER: 10 OF 11

OLS Field Name OLS Field Data
Main Title Observations on the Alteration by Carbaryl of Smooth Muscle Preparation Responses to Norepinephrine.
Author Santolucito, J. A. ; Hassan, A. ; Whitcomb., E. R. ;
CORP Author Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
Year Published 1971
Stock Number PB-277 592
Additional Subjects Norepinephrine ; Pesticides ; Toxicology ; Toxicity ; Amines ; Responses ; Rats ; Interactions ; Experimental data ; Laboratory animals ; Autonomic nervous system ; Adrenergics ; Bioassay ; Reprints ; Carbaryl ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB-277 592 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 1p
Abstract
The present experiment was an attempt to determine whether carbaryl interacts directly with adrenergic mechanisms. Motility response patterns to norepinephrine (NE) in conjunction with alpha- and beta-receptor blocking agents were recorded from isolated preparations of uteri from ovariectomized rats and intestinal segments from rats and rabbits. It is concluded that carbaryl can interact with adrenergic receptors behaving as a beta-sympathomimetic in uterine preparations and as an alpha-blocking agent in intertinal segments.