||Effect of DDT on Antibody Response to Typhoid Vaccine in Rabbits and Man.
Shiplov, J. ;
Graber, C. D. ;
Keil, J. E. ;
Sandifer., S. H. ;
||Medical Univ. of South Carolina, Charleston. ;Environmental Protection Agency, Washington, D.C.
Experimental data ;
Laboratory animals ;
Toxic substances ;
Salmonella typhi ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
DDT-dosed humans and animals injected with Salmonella typhi vaccine produced O, H and Vi agglutinin titers somewhat higher than controls (no DDT). This is in contrast to an earlier report that DDT-fed animals injected with this vaccine experienced a 30% decrease in antibody titre to whole organisms. Immunoglobulin levels in human volumteers were unaffected by DDT ingestion.