Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Value of Studying the Mutagenic and Embryonic Properties of Pesticides for Toxicological-Hygienic Assessment (Znachenie Issledovanii Mutagennykh i Embriotoksicheskikh Svoistv Pestitsidov dlya ikh Toksikologo-Gigienicheskoi Otsenki).
Author Samosh, L. V. ; Pilinskaya, M. A. ; Martson, L. V. ; Kurinnyi., A. I. ;
CORP Author Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1968
Report Number EPA-TR-73-338;
Stock Number PB-261 557-T
Additional Subjects Pesticides ; Toxicity ; Genetics ; Mutagens ; Embryology ; Tables(Data) ; USSR ; Translations ; Cineb ; Cirame ; Maneb ; Manganese ethylene bisdithiocarbamate
Library Call Number Additional Info Location Last
NTIS  PB-261 557-T Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 13p
In experiments on the bone marrow of mice and a leukocyte culture of human peripheral blood, the cytogenetic activity of cineb, cirame and maneb was revealed. Their embryotoxic effect on rats was shown in comparatively high doses, not toxic for the adult organism. This indicates potential danger of these substances according to both indices. Genetic studies for hygienic purposes must be conducted on biological subjects far removed from man, in particular, on insects. The potential and possible actual genetic danger of pesticides can be assessed on the basis of comparing data from tests on human cells 'in vitro' and on the entire organism of laboratory animals.