||Health Effects Research Lab., Research Triangle Park, NC. ;Environmental Monitoring and Services, Inc., Chapel Hill, NC.;Rockwell International Corp., Chapel Hill, NC.
The purpose of the study was to determine whether gender or race differences in ozone (O3) response exist among white and black, males and females, and to develop concentration-response curves for each of the gender-race groups. Three hundred seventy-two subjects (n>90 in each gender-race group), ages 18 to 35 yr, were exposed once for 2.33 h to 0.0 (purified air), 0.12, 0.18, 0.24, 0.30, or 0.40 ppm O3. Lung function and symptom responses were expressed as percent change from baseline and analyzed using a nonparametric two factor analysis of variance. Three primary variables were analyzed: FEV sub 1, specific airway resistance (SRaw), and cough. Statistical analysis demonstrated no significant differences in response to O3 among the individual gender-race groups.