||Use of Whole Embryo Culture for Evaluating Toxicity and Teratogenicity.
Sadler, T. W. ;
Warner, C. W. ;
||North Carolina Univ. at Chapel Hill. School of Medicine.;Health Effects Research Lab., Research Triangle Park, NC.
In vitro analysis ;
Environmental surveys ;
Economic analysis ;
Laboratory animals ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The use of rodent embryos cultured in vitro for the evaluation of the teratogenicity of compounds is discussed in detail. Time and concentration of exposure are delineated as factors of importance, as well as metabolism and embryonic stage. The economic feasibility of using such systems is estimated.