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OLS Field Name OLS Field Data
Main Title Imaging the Brain with Optical Methods [electronic resource] /
Author Roe, Anna W.
Publisher Springer New York,
Year Published 2010
Call Number RC321-580
ISBN 9781441904522
Subjects Medicine. ; Neurosciences. ; Neurology. ; Nanotechnology.
Internet Access
Description Access URL
Collation online resource.
Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes
Casting Light on Neural Function: A Subjective History -- Fluorescent Sensors of Membrane Potential that Are Genetically Encoded -- The Influence of Astrocyte Activation on Hemodynamic Signals for Functional Brain Imaging -- Somatosensory: Imaging Tactile Perception -- How Images of Objects Are Represented in Macaque Inferotemporal Cortex -- Optical Imaging of Short-Term Working Memory in Prefrontal Cortex of the Macaque Monkey -- Intraoperative Optical Imaging of Human Cortex -- Using Optical Imaging to Investigate Functional Cortical Activity in Human Infants -- In Vivo Dynamics of the Visual Cortex Measured with Voltage Sensitive Dyes -- Fast Optical Neurophysiology -- Two-Photon Laser Scanning Microscopy as a Tool to Study Cortical Vasodynamics Under Normal and Ischemic Conditions. The technology of detecting and interpreting patterns of reflected light has reached a remarkable degree of maturity that now permits high spatial and temporal resolution visualization at both the systems and cellular levels. There now exist several optical imaging methodologies, based on either hemodynamic changes in nervous tissue or neurally-induced light scattering changes, that can be used to measure ongoing activity in the brain. Imaging the Brain with Optical Methods presents the history of optical imaging and its use in the study of brain function, and the rapidly developing optical technologies and their applications that have recently developed. These include intrinsic signal optical imaging, near-infrared optical imaging, fast optical imaging based on scattered light, optical imaging with voltage sensitive dyes, and 2 photon imaging of hemodynamic signals. In total, this volume captures a profile of the current state of optical imaging methodologies and their contribution towards understanding the spatial and temporal organization of cerebral cortical function. Imaging the Brain with Optical Methods will be highly valuable for researchers and clinicians interested in brain imaging methods and brain function, including advanced undergraduates, and doctoral students, neuroscientists, physicists, psychologists, bioengineers, neurologists, psychiatrists, and neurosurgeons. About the author: Dr. Anna W. Roe is a professor of psychology and radiology at Vanderbilt University. She has developed optical methods for studying brain function and specializes in how our brain builds real vs. illusory percepts of the world.