Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Ozone dosimetry predictions for humans and rats. {microfiche}
Author Overton, J. H. ; Graham, R. C. ; McCurdy, T. R. ; Richmond, H. M.
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;NSI Technology Services Corp., Research Triangle Park, NC.
Publisher Carnegie Mellon University, The Robotics Institute,
Year Published 1991
Report Number EPA/600/1-90/009
Stock Number PB91-113852
Additional Subjects Dosimetry ; Ozone ; Rats ; Humans ; Air pollution ; Exposure ; Lung ; Risk assessments ; Mathematical models ; Physiology ; Respiratory diseases ; Ventilation ; Respiration ; Dosage ; Concentration(Composition) ; Simulation ; Comparison
Library Call Number Additional Info Location Last
NTIS  PB91-113852 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 40 p. : ill. ; 28 cm.
The report summarizes ozone (O3) dosimetry model predictions for rats and humans under several different scenarios based on the most recent empirical data and theoretical considerations in the field of O3 dosimetry. The report was prepared at the request of the Office of Air Quality Planning and Standards (OAQPS) as an input to be considered by scientists participating in a chronic lung injury risk assessment project for O3. As indicated in the report a number of judgments and assumptions had to be made to obtain the dosimetry predictions. In addition to presenting the simulation results, the O3 dosimetry model used to make the predictions is discussed and the choice or method of selecting important physiological parameters explained. This includes anatomical dimensions, choices of rat and human ventilatory parameters, and the method of estimating human and rat upper respiratory tract uptake. Finally, a comparison of simulation results to recent experimental dosimetry results is discussed.
"November 1990."