||Developmental and Behavioral Effects of Early Postnatal Exposure to Triethyltin in Rats.
Reiter, Lawrence W. ;
Heavner, Glendora B. ;
Dean, Karen F. ;
Ruppert, Patricia H. ;
||Health Effects Research Lab., Research Triangle Park, NC.
Laboratory animals ;
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On day 5 of postnatal life, rat pups received a single injection of triethyltin and were later tested for a variety of developmental and adult behaviors. The results indicate that a single exposure to TET in the developing rat, unlike the adult, produces permanent alterations in both brain and behavior. Acute postnatal exposure to toxicants may have general applicability as a model for developmental neurotoxicity.