Record Display for the EPA National Library Catalog
RECORD NUMBER: 14 OF 30
|OLS Field Name||OLS Field Data|
|Main Title||Effect of Benomyl on the Reproductive Development of Male Rats.|
|Author||Carter, S. D. ; Hein, J. F. ; Rehnberg, G. L. ; Laskey, J. W. ;|
|CORP Author||Health Effects Research Lab., Research Triangle Park, NC.|
|Additional Subjects||Toxicology ; Fungicide ; Reproductive systems ; Laboratory animals ; Rats ; Pesticides ; Environmental surveys ; Exposure ; Carbamates ; Reprints ; Toxic substances ; Benomyl ; Benzimidazole carbamic acid/methyl-(butylcarbamoyl)|
Benomal, a systemic fungicide, was administered to male Sprague-Dawley rats during the prepubertal, pubertal, or postpubertal stage of reproductive development. Animals received 5 or 10 daily treatments of 0, 125, 200, 250, 500, or 1000 mg benomyl/kg-d by gavage. Observations were made at selected intervals after exposure and included hemotological parameters, body weight, tissue weights, total epididymal sperm counts, vas deferens sperm concentrations, serum follicle-stimulating hormone (sFSH) levels, and testicular histology. Data presented here suggest that there is an age-related difference in sensitivity to benomal.