Record Display for the EPA National Library Catalog

RECORD NUMBER: 4 OF 4

OLS Field Name OLS Field Data
Main Title Sensitivity, Specificity and Accuracy of the Arabidopsis Assay in the Identification of Carcinogens.
Author Redei, G. P. ; Acedo, G. N. ; Andhu, S. S. ;
CORP Author Missouri Univ.-Columbia.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-R-807892; EPA-600/D-84-105;
Stock Number PB84-182195
Additional Subjects Carcinogens ; Bioassay ; Bacteria ; In vitro analysis ; In vivo analysis ; Sensitivity ; Mutagens ; Identifying ; Accuracy ; Arabidopsis multilocus ; Bioindicators
Holdings
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Status
NTIS  PB84-182195 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 33p
Abstract
The paper compares the sensitivity, specificity and accuracy of Arabidopsis multilocus assay with several other in vitro and in vivo bioassays. Sensitivity was defined as a percentage of the carcinogens correctly identified as mutagens. Specificity was calculated by multiplying with 100 the fraction of the number correctly identified 'non-carcinogens'/total number of 'non-carcinogens' unambiguously classified. Accuracy represents the fraction of the correct answers/all unambiguous test, multiplied with 100. These parameters were estimated in Arabidopsis by testing 37 carcinogen/non-carcinogen pairs of chemicals. The overall sensitivity of Arabidopsis assay was higher than any of the bioassays employed in the Internation Collaborative Program.