The manual summarizes information that will aid in identifying and controlling release hazards specific to the South Coast Air Quality Management District (SCAQMD) of southern California. The SCAQMD has been considering a strategy for reducing the risk of a major accidental air release of toxic chemicals. The strategy, which will serve as a guide to industry and communities, includes monitoring activities associated with the storage, handling, and use of certain chemicals. Carbon tetrachloride has an immediately dangerous to life and health (IDLH) concentration of 300 ppm, making it a moderate acute toxic hazard. To reduce the risk associated with an accidental release of carbon tetrachloride, the potential causes of releases from processes using carbon tetrachloride in the SCAQMD must be identified. Such measures include recommendations on: plant design practices; prevention, protection, and mitigation technologies; and operation and maintenance practices. Conceptual costs of possible prevention, protection, and mitigation measures are estimated.