Record Display for the EPA National Library Catalog

RECORD NUMBER: 20 OF 24

OLS Field Name OLS Field Data
Main Title Subacute Ethanol Consumption Reverses p-Xylene-Induced Decreases in Axonal Transport.
Author Padilla, S. ; Lyerly, D. L. ; Pope, C. N. ;
CORP Author Environmental Protection Agency, Research Triangle Park, NC. Neurotoxicology Div. ;Burroughs Wellcome Co., Research Triangle Park, NC. ;Northeast Louisiana Univ., Monroe. Toxicology Program.
Publisher c1992
Year Published 1992
Report Number EPA/600/J-92/425;
Stock Number PB93-141240
Additional Subjects Toxicology ; Xylenes ; Ethyl alcohol ; Axons ; Nervous system ; Rats ; Neurons ; Protein synthesis ; Environmental exposure ; Reprints ; Axonal transport
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB93-141240 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/12/1993
Collation 11p
Abstract
Organic solvants, as a class, have been implicated as neurotoxic agents in humans and laboratory animals. The study was designed to assess the interaction between subacute ingestion of moderate levels of ethanol and the p-xylene-induced decreases in protein and glycoprotein synthesis and axonal transport in the rat optic system. The results indicated that animals maintained on 10% ethanol as a drinking liquid show less p-xylene-induced neurotoxicity than animals receiving no ethanol supplement.