Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Sister Chromatid Exchange and Genotoxicity Measurements Using Polychaete Worms.
Author Pesch, G. G. ;
CORP Author Environmental Research Lab., Narragansett, RI.
Publisher c1990
Year Published 1990
Report Number EPA/600/J-90/013;
Stock Number PB90-217647
Additional Subjects Marine biology ; Chromosomes ; Carcinogens ; Mutagens ; Reprints ; Sister chromatid exchange ; Mutagenicity tests ; Polychaeta
Library Call Number Additional Info Location Last
NTIS  PB90-217647 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 08/27/1990
Collation 9p
Contaminants entering coastal marine environments may affect the genetic constitution of exposed organisms by causing shifts in gene pool composition through selective pressures or by acting directly on the genetic material to cause damage. The latter problem is referred to as genotoxicity. The article reviews genotoxicity studies done with marine polychaetes, with special emphasis on the chromosomal response of sister chromatid exchange (SCE). Chromosomal responses have been studied in the polychaete Neanthes arenaceodentata exposed to pure compounds and radiation, and in the polychaete Nephtys incisa exposed to a complex mixture. All of the published results to date have come from two laboratories, the U.S. National Laboratory at Livermore, California (Harrison and co-workers) and a U.S. EPA Laboratory at Narragansett, RI (Pesch and co-workers). The article reviews and summarizes the work in the context of assessing risks associated with mutagens and carcinogens in marine environments.