Record Display for the EPA National Library Catalog
RECORD NUMBER: 6 OF 17
|OLS Field Name||OLS Field Data|
|Main Title||Health assessment document for polychlorinated dibenzo-p-dioxins.|
|Author||Basu, D. K. ; Mukerjee, D. ; Neal, M. W. ; Olson, J. R. ; Hee, S. Q.|
|CORP Author||Environmental Protection Agency, Cincinnati, OH. Environmental Criteria and Assessment Office.|
|Publisher||U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office,|
|Subjects||Dioxins--Toxicology. ; Hazardous wastes.|
|Additional Subjects||Hazardous materials ; Industrial hygiene ; Toxicology ; Environmental surveys ; Public health ; Assessments ; Exposure ; Carcinogens ; Mutagens ; Laboratory animals ; Chemical properties ; Chlorine organic compounds ; Water pollution ; Air pollution ; chemical analysis ; Sampling ; Sources ; Transport properties ; Ecology ; Occupational safety and health ; Toxic substances ; Environmental health ; Polychlorinated dibenzodioxins ; Pharmacokinetics ; Path of pollutants ; Dioxin(Herbicides) ; Dibenzodioxin/tetrachloro ; Dibenzodioxin/pentachloro ; Dibenzodioxin/hexachloro ; Bioaccumulation|
|Collation||612 pages : illustrations ; 28 cm|
The health assessment document on polychlorinated dibenzo-p-dioxins discusses multimedia environmental issues pertaining to the most toxic chlorinated dioxins, namely, 2,3,7,8-tetrachloro-; 1,2,3,7,8-pentachloro-; 1,2,3,6,7,8-hexachloro-; and 1,2,3,7,8,9-hexachlorodibenzo-p-dioxins. Scientifically valid data essential for human health risk assessment purposes from an extensive literature search have been compiled and discussed critically. Discussions are based on physiochemical properties and analytical methodologies; stability and degradation; production, use, synthesis; environmental resources and environmental levels; environmental ffate and transport; degradation; bioaccumulation and bioconcentration factors; ecological effects; various aspects of toxic effects from acute, subchronic and chronic exposures in experimental animals and humans; pharmacokinetics and mechanism of toxic effects; teratogenicity and reproductive effects; mutagenicity and carcinogenecity. Based on this review, critical studies have been identified and utilized for estimating the unit risk.
"Final report." "September 1985." Includes bibliographical references (pages 15-1-15-111). "EPA/600/8-84/014F." Microfiche.