Record Display for the EPA National Library Catalog

RECORD NUMBER: 10 OF 19

OLS Field Name OLS Field Data
Main Title Mechanisms of pesticide degradation /
Author Matsumura, Fumio.
Other Authors
Author Title of a Work
Moseman, Robert F.
CORP Author Wisconsin Univ., Madison. Dept. of Entomology.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
Year Published 1978
Report Number EPA-600/1-78-065; R-801060; EPA-R-801060
Stock Number PB 289 776
OCLC Number 34496308
Additional Subjects Pesticides ; Toxicity ; Degradation ; Molecular structures ; Anaerobic processes ; Chlorine organic compounds ; Laboratory animals ; Insecticides ; Separation ; Camphene ; Chemical analysis ; Bioassay ; Public health ; Toxaphene ; Chlordimeform ; Formamidine/N-(chloro-tolyl)-N-N-dimethyl ; Poly(bornane/chloro) ; Poly(bornene/chloro) ; Poly(tricyclene/chloro)
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=2000ZPF0.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBD ARCHIVE EPA 600-1-78-065 Headquarters Library/Washington,DC 08/09/2010
EJBD  EPA 600-1-78-065 c.1 Headquarters Library/Washington,DC 04/28/2014
EKAM  EPA-600/1-78-065 Region 4 Library/Atlanta,GA 09/27/1996
EKBD  EPA-600/1-78-065 Research Triangle Park Library/RTP, NC 04/12/1996
EKCD  EPA-600/1-78-065 CEMM/GEMMD Library/Gulf Breeze,FL 05/29/2018
ELDD  EPA-600/1-78-065 CCTE/GLTED Library/Duluth,MN 08/25/2000
NTIS  PB-289 776 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation vii, 32 pages : illustrations ; 28 cm.
Abstract
This research project was initiated with the overall objective of determining (1) the chemical structures of toxic components of toxaphene, (2) to study anaerobic metabolism to degrade toxaphene and other pesticides, and (3) to understand toxic action mechanism of chlordimeform. As a result of intensive efforts the molecular structures of three of the most toxic principles of toxaphene were identified. Together these components comprise at least 70% of toxaphene's toxicity toward mice. This is the first time that the structure of toxic components of toxaphene became apparent despite the widespread use (over 1 billion pounds, which is comparable to DDT) of toxaphene in the last 3 decades. Toxaphene on the other hand degrades relatively faster than other chlorinated pesticides such as DDT and dieldrin. The reason for it is that toxaphene is susceptible to reductive degradative forces. Chlordimeform was found to affect amine regulatory mechanisms in animals. Such actions explain some of the subtle effects of this pesticide on animals. Inasmuch as that biogenic amines are known to play many important biological roles such as controlling emotion, behavior and circulatory functions of the body.
Notes
EPA Project Officer: Robert F. Moseman, Analytical Chemistry Branch, Environmental Toxicology Division, Health Effects Research Laboratory. Prepared by the Dept. of Entomology, University of Wisconsin, under Grant No. R-801060. "November 1978." Includes bibliographical references (pages 24-25).